NFE2L2 and Alzheimer disease: On the other hand, SFN’s effects through the Nrf2 pathway, such as the activation of genes and molecules with antioxidant, anti-inflammatory, and anti-apoptotic properties, have been suggested as the main mechanisms behind SFN’s beneficial effects against neurotoxicity, particularly against neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and multiple sclerosis (MS) [33].