In the present study, among the various heart conditions, only non-ischemic heart diseases such as heart valve disease, atrial fibrillation and arrhythmias were significantly correlated with the prevalence of insomnia; however, the pathogenesis of these conditions is inflammatory in nature as well, and is expressed in particular by an altered neutrophil to lymphocyte ratio and high levels of C-reactive protein, which are responsible for the comorbidities associated with hypertension [63,64,65]. This evidence concerns the gene CRP and Hypertension.