MAP1LC3A and lung carcinoma: Per its effects on mitophagy, the fluorescence labeling assay showed significant colocalization of the autophagy marker LC3 and mitochondria in lung cancer cells after MTERF3 knockdown (Figure 9E), and the green/red (LC3/mitochondria) ratio was significantly increased in MTERF3 knockdown cells (Figure 9F,G).