Macrophages have been implicated in the chemotaxis of γδ T cells to the infection site via secretion of IP-10, inducing changes in chemokine expression pattern [106]; after being trafficked to the pulmonary compartment, Vγ9Vδ2 T cells can differentiate into IFNγ-, perforin-, and granulysin-producing cells, thus reducing bacterial burden and increasing immune resistance against M. tuberculosis [36,103]. This evidence concerns the gene IFNG and infection.