CD4 and intrahepatic cholangiocarcinoma: The CD4+/CD8+ T cell ratio of the ICC patients was also higher than that in the HCC (p = 0.001) and BLD (p = 0.007) patients, while there was no significant difference observed between the HCC and BLD groups (ICC: HCC: BLD = 2.20 vs. 1.79 vs. 1.73, Figure 1B).