PDCD1 and obesity due to melanocortin 4 receptor deficiency: Interestingly, a decreased percentage of PD-1+ cells within the Th17 subset was detected in the OB group (37% ± 9.9), with an emphasis on Class III obesity (34% ± 6.5), compared to nOB (44% ± 15.4, p > 0.05; Supplementary Table S4), in addition to the Th1/17 cells (nOB: 64% ± 17.6 vs. OB: 58% ± 11.5, p > 0.05; Supplementary Table S4).