CD4 and obesity due to melanocortin 4 receptor deficiency: CCR5−CCR6− Th cells comprised approximately 52% ± 9.0 of the CD4+ T cells in the nOB group, while in OB groups they comprised 39% ± 9.8 of the CD4+ T cell compartment (p < 0.05), even among obesity classes and metabolic groups (Figure 6D and Supplementary Table S4).