LILRB4 and neoplasm: It has been reported that LILRB4 coordinates MDSC polarization by inducing the differentiation of M-MDSCs toward a tumor-promoting M2 phenotype, and that high expression of LILRB4 decreases the expression of anti-tumor miRNAs in MDSCs, including miR-1a-3p, miR-133a-3p and miR-206-3p [40].