GRB2 and cancer: Other HSCR-associated pathways (Figure 4) obtained by filtering out from CTD and Malacards were central carbon metabolism in cancer, thyroid cancer; B cell receptor signaling, signaling by ERBB4, GRB2 events in ERBB2 signaling, SHC1 events in ERBB2 signaling, SHC1 events in ERBB4 signaling and the Fc epsilon RI signaling pathway.