Other HSCR-associated pathways (Figure 4) obtained by filtering out from CTD and Malacards were central carbon metabolism in cancer, thyroid cancer; B cell receptor signaling, signaling by ERBB4, GRB2 events in ERBB2 signaling, SHC1 events in ERBB2 signaling, SHC1 events in ERBB4 signaling and the Fc epsilon RI signaling pathway. The gene discussed is GRB2; the disease is thyroid cancer.