Interestingly, 11 out of these HSCR-associated pathways (Table 5) were in the Top 20 of the most significant enriched terms in the categories KEGG (miRPathDB) and Reactome (miRPathDB), to know cellular responses to stress, cellular senescence, cytokine signaling in immune system, disease, diseases of signal transduction, immune system, microRNAs in cancer, pathways in cancer, PIP3 activates AKT signaling, signal transduction and signaling by interleukins. The gene discussed is EDNRB; the disease is cancer.