In such cases, the analysis of other genes frequently mutated in individuals with non-syndromic hearing loss, such as STRC, MYO15A, MYO7A, TECTA, POU4F3, KCNQ4, SLC26A4, OTOF, MT-RNR1, MITF, and WFS1, or more extensive genetic testing through full-exome sequencing should be taken into consideration in order to both highlight possible synergies in determining the audiological phenotype and provide correct genetic counseling to parents [39,40]. This evidence concerns the gene SLC26A4 and hearing loss disorder.