CDH1 and CDH1-related diffuse gastric and lobular breast cancer syndrome: According to the consensus guidelines established for HDGC, women who meet specific criteria, including those diagnosed with bilateral LBC, regardless of family cases of LBC prior to the age of 50, or women diagnosed with unilateral LBC with other cases of LBC in the family, characterized below 45 years, meet the necessary criteria for CDH1 genetic testing [40].