GJB2 and hearing loss disorder: Genetic studies of the GJB2 gene from the Latin American hearing loss population confirmed the importance of GJB2 variants as a frequent cause of non-syndromic sensorineural hearing loss, gave further support for the pathogenicity of many GJB2 variants and contributed to the description of novel pathogenic variants [48,88,89,90,91,92,93,94,95,96,97,98,99].