CTCF and cancer: This is equivalent to the window size with which we compute the running average DeepLIFT scores; (2) altering input sequence lengths: we explore how motif enrichment changes with input sequences of various lengths, specifically 5000, 10,000, and 20,000 base pairs (bps); (3) sampling background control sequences from constitutive CTCF sites: this entails studying the effect of sampling constitutive sites on motif rankings; (4) sampling foreground sequences from cancer-specific CTCF sites: we investigate the impact on motif rankings when gained sites are sampled.