Several exogenous and autoantigens have been implicated in the initiation of an immune response and the induction and progression of atherosclerosis, including cytomegalovirus, hepatitis C virus, human immunodeficiency virus, and others, as well as autoantigens including heat shock proteins and LDL/oxLDL and its major protein apolipoprotein B-100 (ApoB-100) [13,136]. Here, APOB is linked to atherosclerosis.