Most genes were upregulated in DLBCL, and among the upregulated PRGs, PYCARD, IRF1, GZMA, GSDMD, GSDMC, GPX4, CHMP2A, CASP5, CASP1, Il-18, and BAK1 showed an amplified CNV status, suggesting a significant relationship between the PRG expression and CNVs [102]. The gene discussed is GART; the disease is diffuse large B-cell lymphoma.