ALB and Hyperglycemia: Therefore, the main aims of this study were: (1) to reveal how simultaneous presence of stearic acid (SA) and glucose in pathophysiological concentrations during in vitro glycation of HSA affects HSA-SH reactivity and content; (2) to find whether the joint action (synergy) of SA and glucose could affect the structural changes of HSA and formation of AGEs during glycation; (3) to assess if there is a tight connection between HSA functions and ubiquitous ligands (FAs and glucose) on their possible synergistic contribution in different vascular disorders (hyperglycemia, hyperlipidemia, etc.).