Higher levels of ET-1 in patients with AF, compared to age- and sex-matched healthy volunteers without AF (2.62 pg/mL vs. 1.57 pg/mL; p < 0.001).Lower ET-1 levels prior ablation associated with freedom of AF in the follow-up period of 3 months (2.57 pg/mL vs. 2.96 pg/mL; p = 0.02)(MCP-1 plasma levels increased significantly after ablation independent from AF recurrence; CGA levels increased significantly only in patients without recurrence towards the level of healthy controls). Here, EDN1 is linked to atrial fibrillation.