Moreover, loss of parafibromin staining was also found in sporadic ossifying fibromas, pointing towards an underlying pathogenic mechanism involving CDC73, not only in parathyroid, but also in jaw tumours [73], or in various kidney tumours, pancreatic carcinomas, as well as breast, lung, gastric, and colorectal neoplasia [74,75]. The gene discussed is CDC73; the disease is exocrine pancreatic carcinoma.