Galnt3-deficient (Galnt3−/−) male mice show retarded growth, infertility, and increases in trabecular bone volume and cortical bone area, while Galnt3−/− female mice show normal growth and no bone phenotypes [11], although both male and female Galnt3−/− mice show hyperphosphatemia and reduction in the serum levels of intact Fgf23 [12]. This evidence concerns the gene FGF23 and hyperphosphatemia.