Both CEA and CA-19-9 were notably elevated in human colorectal adenocarcinoma Caco-2 cells, but not in the blood and colonic tissue from HFHSD-induced diabetic mice and ND-fed healthy mice after five consecutive miR-10a/b mimic injections at 5 months (Figure 2B,C). Here, CEACAM5 is linked to colorectal adenocarcinoma.