INS and type 2 diabetes mellitus: The high degree of superposition of type 2 diabetes and obesity also favored using (for a time) the concept ‘diabesity’ to define this dual synergic (and syndromic) condition [74,75,76]; however, obesity has been largely (and inadequately) attributed to just ‘excessive energy intake’, which, consequently, generates an ‘energy imbalance’ that translates into an inordinate accumulation of fat [77], whilst diabetes had a better-known (and assumedly “different”) explanation based on glucose/insulin interactions.