BRAF and ameloblastoma: Ameloblastomas commonly show the activating mutation V600E in the v-Raf murine sarcoma viral oncogene homologue B (BRAFV600E) located on chromosome 7q34; BRAF is a key member of the mitogen-activated protein kinase (MAPK) signaling pathway, which plays a crucial role in cell growth and proliferation [10,11,12,13,14,15,16,17].