KLK2 and prostate adenocarcinoma: In fact, KLK2 was highly expressed in PRAD compared with non-transformed tissue (5956.5 and 4175.26 transcripts per million (TPM), respectively), which comprised a >1.4-fold change, as displayed in Figure 1B. Once the selective expression of KLK2 in PRAD was confirmed, we aimed to evaluate their role in cell survival.