HLA-DRB1 and hepatocellular carcinoma: Another publication analysing 12 case-control studies (2030 HCC patients and 2817 relevant controls) confirmed that HLA-DRB1*12 and HLA-DRB1*14 are risk factors for HCC development, while it was observed that HLA-DRB1*1 and HLA-DRB1*11 are protective factors [61].