Of the nine studied loci, eight polymorphisms of SHBG-related genes were part of the BC-risk interlocus models, such as rs780093 GCKR, rs17496332 PRMT6, rs3779195 BAIAP2L1, rs10454142 PPP1R21, rs7910927 JMJD1C, rs4149056 SLCO1B1, rs440837 ZBTB10, and rs8023580 NR2F2 (Table 2). Here, PRMT6 is linked to breast cancer.