CDH1 and acute myeloid leukemia: MALAT-1, an lncRNA, was shown to interact with enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH-2) and SUZ-12, the subunits of the polycomb repressive complex 2 (PRC2), which are directly involved in methylation of the cdh1 promoter and thus suppress cdh1 expression in AML [87].