At present, mutation models have been established for genes related to albinism [26], including the zebrafish models of GPR143(OA1) [28], TYR(OCA1a and b) [29,30], OCA2/p(OCA2) [30], TYRP1(OCA3) [31], SLC45A2(OCA4) [30,31,32,33], SLC24A5(OCA6) [34], C10ORF11(OCA7) [35], Hermansky–Pudlak Syndrome [36], Griscelli Syndrome [37,38], and other lysosome-related organelle disorders [39,40,41,42]. Here, TYR is linked to disorder of lysosomal-related organelles.