The knockdown of AKT1 and knockdown of AKT2 decreased the proliferation of both HCC cells, i.e., Hep3B and HuH7, whereas the knockdown of AKT3 did not show a significant alteration in proliferation in comparison to the SCR control in Hep3B cells (Supplementary Figure S3). The gene discussed is AKT1; the disease is hepatocellular carcinoma.