Finally, this study found that miR-145 upregulation was positively associated with SRGAP2 expression, which is a Rho GTPase-activating protein originally identified as regulating neuronal migration and differentiation but more recently identified as a potential chemoregulatory modulator in hepatocellular carcinomas and colorectal cancers [65,66,67]. This evidence concerns the gene SRGAP2 and hepatocellular carcinoma.