Herein, we studied the correlation between reticulocyte maturity indices for the first time, as given by automatic blood cell counters and the mRNA levels of antioxidant enzymes (CAT, GPX1, PRDX2 and SOD1) in reticulocytes from healthy individuals and from patients with HS, β-thal or SCD. This evidence concerns the gene SOD1 and Schnyder corneal dystrophy.