The main fusion genes monitored by qPCR are RUNX1::RUNX1T1 (formerly AML1-ETO, resulting from t(8;21) rearrangement) and CBFB::MYH11 (resulting from inv(16) or t(16;16)) in Core Binding Factor (CBF) AML [56], and PML::RARA in acute promyelocytic leukemias (APLs) [57]. The gene discussed is PML; the disease is acute promyelocytic leukemia.