KCNJ11 and hepatocellular carcinoma: Furthermore, research conducted by Zhang et al. revealed upregulation of the KCNJ11 gene via NF-κB signaling in hepatocellular carcinoma (HCC), a finding observed across multiple HCC cell lines, including Hep3B, MHCC-97H, MHCC-97L, Huh7, SUN-423, and HepG2.