FOLR1 and cancer: On the contrary, the FOLR1 mRNA levels were decreased in six cancers including breast cancer (BRCA), lung squamous cell carcinoma (LUSC), head and neck squamous cell carcinoma (HNSC), kidney chromophobe (KICH), acute myeloid leukemia (LAML), and skin cutaneous melanoma (SKCM) (Figure 4).