PLA2G7 and hypoalphalipoproteinemia, primary, 1: On the other hand, there has been no research concerning the association between allergic conditions and PLA2G7 activity, although increased PLA2G7 activity has been reported in various pathologic conditions, including ischemic stroke, myocardial infarction, familial HDL deficiency, chronic cholestasis, diabetes mellitus, rheumatoid arthritis, essential hypertension, and peripheral vascular disease [20].