In the combination study of oncolytic adenovirus armed with murine chemokine CXCL11 and B7H3 CAR T-cells, it was shown that CXCL11-oAd improves the recruitment of CAR T-cells into the tumor sites and reprograms the immunosuppressive TME in immunocompetent mice C57Bl/6 with glioma GL261. This evidence concerns the gene CXCL11 and neoplasm.