MTOR and fetal growth restriction: In the placenta, this process is essential in early pregnancy, and different obstetric conditions like PE or fetal growth restriction (FGR) seem to be associated with an abnormally increased placental autophagosome formation, mainly related to different pathological factors like hypoxia, endoplasmic reticulum stress, altered mTOR activity, exacerbated inflammation, and abnormal functioning of trophoblasts [19].