For the m6A upregulated and mRNA upregulated genes, GO analysis revealed enrichment in ferrous iron binding, sulfinoalanine decarboxylase activity, aspartate 1-decarboxylase activity, and negative regulation of cell junction assembly and KEGG analysis revealed enrichment in the type 2 diabetes mellitus, adipocytokine signalling, and insulin signalling pathways. The gene discussed is INS; the disease is type 2 diabetes mellitus.