As discussed earlier, Plexin D1 exhibited good diagnostic accuracy in differentiating DM patients from healthy controls (AUC of 0.75), as well as from patients with other autoimmune diseases (AUC of 0.78) and patients with DMD/BMD (AUC of 0.74) in the receiver operating characteristic analyses (ROC) [7]. This evidence concerns the gene PLXND1 and autoimmune disease.