However, this complete AXIN1 inactivation in the benign and malignant teratoma tissues, in combination with FOXE1 c.-522G>C, seemingly necessary, was not enough to induce malignant teratoma development, because a pathogenic somatic BRAF variant (p.Gly469Ala) was exclusively present in the MSO sample. The gene discussed is AXIN1; the disease is teratoma.