This difference was not related to a difference in HER2 or Ki-67 status between the groups, because the percentage of HER2-negative invasive carcinoma NST was similar to the fraction of HER2-negative invasive lobular carcinoma (120/146; 82% versus 28/31; 90%, respectively; p = 0.44). The gene discussed is MKI67; the disease is invasive carcinoma.