TNC and Sepsis: Additionally, as highlighted in the accompanying companion review [1], many conditions other than ACS can present with elevations in serum Tn, including cardiac conditions such as tachyarrhythmia and noncardiac conditions such as pulmonary (e.g., pulmonary embolism), renal (end-stage renal disease), neurologic (e.g., stroke), musculoskeletal (e.g., rhabdomyolysis), oncologic (e.g., when undergoing certain chemotherapies), and GI causes, as well as trauma (e.g., blunt chest trauma) and acute illness (e.g., sepsis) [70,71,72,73].