Moreover, DUSP8 is not exclusively downregulated in LUAD, but it is also downregulated in pancreatic ductal adenocarcinoma (PDAC), kidney renal papillary cell carcinoma (RPCC), and cervical squamous cell carcinomas (CSCC) (Supplementary Fig. S1I), again being associated with poor OS (Supplementary Fig. S1J). Here, DUSP8 is linked to pancreatic ductal adenocarcinoma.