To determine the tumor-suppressive properties of DUSP8 overexpressing cells in vivo, we transplanted A549-DUSP8 OE and A549-EV cells subcutaneously into the right flank of NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) immunodeficient mice. The gene discussed is DUSP8; the disease is neoplasm.