In that study, some NUP98-HOXD13 mice developed myeloproliferative disease at the 4-week post-transplant mark but none progressed to AML (except those engineered to concurrently express the TALE homeobox gene Meis1, a strong mediator of NUP98-associated leukemia [91] during a 6-month study period [92]. Here, HOXD13 is linked to acute myeloid leukemia.