NUP98 and leukemia: In that study, some NUP98-HOXD13 mice developed myeloproliferative disease at the 4-week post-transplant mark but none progressed to AML (except those engineered to concurrently express the TALE homeobox gene Meis1, a strong mediator of NUP98-associated leukemia [91] during a 6-month study period [92].