Strikingly, PRDM1 transcription factor was found to interact with 82Q ATXN1, the mutant protein in spinocerebellar ataxia type 1 (SCA1), and has been found to be expressed at the granule and Purkinje cells of the cerebellum during chicken embryonic and germline development (Lim et al. 2006; Wan et al. 2014b). This evidence concerns the gene ATXN1 and spinocerebellar ataxia type 1.