DAB1 and spinocerebellar ataxia type 37: In this study, by accurately determining the size and configuration of the complex 5ʹ(ATTTT)n–(ATTTC)n–3ʹ(ATTTT)n repeat tract within the DAB1 gene underlying SCA37 pathology by CRISPR/Cas9-mediated enrichment combined with nanopore long-read sequencing, we establish novel genotype–phenotype associations with significant implications for genetic diagnosis.