INS and Renal insufficiency: Studies in adult patients showed that elevated ADMA levels have been associated with various atherosclerosis risk factors such as ageing, hypercholesterolemia, hypertension, diabetes mellitus, insulin sensitivity and renal failure.18 A previous study in children with epilepsy reported a significant positive correlation between ADMA,TG, and LDL-C,27 but as far as we know, no other studies showed a relationship between serum ADMA, endocan and lipid profile in FMF pediatric patients.