LAMP1 and Stroke: In microglia nodules in MS, lysosomal-associated membrane protein 1 (Lamp1)+ lysosomes more often contained oxidized phospholipids (detected using antibody E06) compared to microglia nodules in stroke (MS: 30 of 47 nodules, per donor 68.0% ± 2.8%, stroke: 7 of 29 nodules, per donor 29.1% ± 7.0%, p = 3.2-12), showing that microglia nodules in MS are more involved in phagocytosis of oxidized phospholipids (Fig. 6a-c).