Microglia nodules in MS, compared to microglia nodules in stroke, also upregulated expression of genes previously associated with MS-lesion pathology (HLA-DRB5, ISG15, MX1, after correction HLA-DRB5, ISG15) and MS susceptibility (IFNAR2, also after correction)32,38. The gene discussed is IFNAR2; the disease is stroke disorder.