CD274 and colitis: Mini-endoscopic imaging and histopathological evaluation showed that signs of colonic mucosal inflammation were observed in colitis mice and alleviated with PD-L1-Fc, PD-L1-Fc/Oxi-αCD nanoparticles or PD-L1-Fc/PLGA nanoparticles treatment (Fig. 4F, G and Supplementary Fig. 13D, E).