Moreover, erastin as well as RSL3 treatment increased the expression of a set of ferroptosis-related proteins, including iron regulatory protein 1 (IRP1), heme oxygenase 1 (HO-1), transferrin receptor 1 (TFR1), ferritin, and solute family 7 member 11 (SLC7A11), which collectively confirms the ferroptosis-inducing effects of erastin and RSL3 in GBM cells. This evidence concerns the gene HMOX1 and glioblastoma.