G6PD and hyperinsulinemic hypoglycemia, familial, 4: Therefore, WHO guidelines in 2016 recommend a 14-day primaquine regimen with 0.25 to 0.5 mg base per kilogram for patients without G6PD deficiency (“G6PD normal”), and an 8-week primaquine regimen with 0.75 mg base per kilogram for G6PD deficient patients when administered under medical supervision [8].