RPL35A and cholangiocarcinoma: To investigate the role of RPL35A on the progression of CCA, the expression of RPL35A was examined by RT-qPCR in four CCA cells (HCCC-9180, HUCCT1, QBC-939, and RBE) and human intrahepatic biliary epithelial cell line (HIBEC cells), which indicated that RPL35A was wide overexpressed in CCA cell lines (Fig. 1E).