The KEGG pathway enrichment analysis implied that these upregulated genes in the ICD high subtype were frequently enriched in cytokine-cytokine receptor interaction, chemokine signaling pathway, viral protein interaction with cytokine and cytokine receptor, B cell receptor signaling pathway primary immunodeficiency, and intestinal immune network for IgA production, most of which were involved in activities of immunity (Fig. 2C). The gene discussed is CD79A; the disease is Immunodeficiency.